Depura® Regenerating Hair Serum

4.5/5Excellent
  • 30 seconds a day. Roll directly onto the scalp. Leave in.

  • DHT. Collagen ‘cage’. Blocked follicles.* Treated at the root.

  • Root care. Growth support.* Four actives. No side effects, no minoxidil.

The system that tackles all 3 mechanisms of hair loss in one application.

£29.90

Review the selected purchase terms at checkout.

Limited availability

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🌍FREE shipping over £44

Jhon R.

3 months with Depura

“I’ve been using it for 3 months… nobody believes I was losing my hair!”
Jhon R.Verified Purchase
99-day money-back guarantee

*Ingredient research. DHT findings are from laboratory studies.

See the ritual. Hear their stories.

The Follicular Awakening System™

Three phases. One daily application.

  1. Conceptual illustration of a dormant, miniaturised hair follicle surrounded by dense collagen fibres and symbolic DHT molecules.
    Applying Depura directly to the scalp along the hairline

    1. Wake up the growth cycle.

    3% Redensyl™ + 2% AnaGain™ are studied for follicle activity and growth. The formula also contains 3% rosemary; rosemary extract has inhibited the enzyme that makes DHT in laboratory research.*

  2. Conceptual illustration of the collagen cage loosening around the follicle.
    Close-up of the Depura roll-on at the temple

    2. Focus on the collagen ‘cage’.

    2% Aminexil. Root-care research examines the tissue around the follicle and its elasticity. The ‘collagen cage’ describes collagen hardening around the root.*

  3. Conceptual illustration of a vigorous hair follicle with a thicker hair shaft.
    Man wearing sunglasses in an open-top car

    3. Apply daily. Stay consistent.

    Roll onto your scalp in 30 seconds each evening. Massage and leave in. Track your progress over 3–6 months. Your hair grows in cycles; give your routine time.

*Ingredient evidence, not a clinical trial of the finished Depura serum. Results vary.

Studies & full ingredient list

Rosemary & DHT. Rosemary leaf extract inhibited 5α-reductase, the enzyme involved in DHT production, in laboratory research. This does not establish DHT-blocking effects of the finished Depura serum in people. Read the study.

Collagen & Aminexil. Published ingredient research describes Aminexil in relation to the elasticity of tissue around hair roots. The “collagen cage” is a simplified explanation of collagen hardening around the follicle, not proof that Depura reverses fibrosis. Read the research.

AnaGain™. The supplier reports a 78% improvement in the ratio of growing to resting hairs after 3 months. This is not a 78% increase in total hair count. Read the ingredient research.

Redensyl™. The supplier reports over 10,000 new hairs on average after 3 months in its ingredient study. This is not a result measured for Depura. Read the ingredient research.

Full ingredient list

Aqua, Propanediol, Butylene Glycol, Propylene Glycol, Glycerin, Rosmarinus Officinalis (Rosemary) Leaf Extract, Diaminopyrimidine Oxide, Pisum Sativum Sprout Extract, Phenoxyethanol, Sodium Benzoate, Sodium Metabisulfite, Larix Europaea Wood Extract, Glycine, Zinc Chloride, Camellia Sinensis Leaf Extract, Trigonella Foenum-Graecum Seed Extract.

Check your bottle’s label for the applicable formula.

In trusted hands.Italian pharmacists on Depura.

Your comeback, one day at a time.

Illustrative comparison of Cesare, labelled Day 1 and Month 6. The Before portrait is digitally altered.
  1. Start

    Take your first photo.

  2. 3 months

    Check your progress.

  3. 6 months

    Compare your photos.

More than hair. Their confidence, back.

Giorgio V. — published Depura photo
Giorgio V.

The hairline I worried about at school.

“My receding hairline had been wearing down my confidence since school. Depura isn’t greasy and takes 30 seconds a day. My hair looked fuller after 10 weeks.”
Marco D. — published Depura photo
Marco D.

I’d already tried the oils.

“I’d wasted money on oils and shampoos that did nothing. With Depura, I noticed the first new hairs within a few weeks and much less shedding.”
Roberto G., 32 — published Depura photo
Roberto G., 32

I see it in the mirror.

“After a month of using the roll-on every evening, I was already shedding less. At three months, my hairline was visibly filling in.”

3 customer stories

Individual experiences vary.

Fuller hair. Less effort. Better value.

Compare results, ease of use and cost.

Click or tap to enlarge
Comparison sources & context

Spartan’s product page; Regaine’s product information; NHS hair transplant guidance. The options differ in purpose and use. No head-to-head study establishes Depura as more effective than these options.

Try it for 99 days.Your comeback. Or your money back.

Make Depura part of your evening. If you’re not happy with your progress, claim your refund within 99 days of purchase. Your first order is backed by our guarantee.

How your 99-day guarantee works

For your first purchase: use Depura daily as directed for at least 50 days and request your refund within 99 days of purchase. Keep your order details and return all packaging, including empty bottles and any remaining bottles from your order.

Return postage is your responsibility; original shipping charges are not refundable. Full eligibility and the return process are set out in our refund policy. The 99-day guarantee does not extend to the full six- or nine-month programme.

Read the full guarantee terms

Before you begin.

Start my hair comeback
Is Depura right for my stage of thinning?

Depura is designed as a daily scalp-care routine for the first signs of thinning at the hairline, crown or parting. If hair loss is sudden, patchy or extensive, a GP or dermatologist can help you understand the cause.

How do I use the roll-on?

Shake, roll onto dry thinning areas and massage gently. Leave on for at least six hours. Use daily and follow your bottle’s directions.

Will it leave my hair looking greasy?

The serum is designed as lightweight, leave-in scalp care. Roll it directly onto the scalp, massage gently and let it absorb. You can get on with your day.

Does it contain minoxidil or alcohol?

Neither minoxidil nor alcohol appears in the current published ingredient list. Check your bottle’s label for the applicable formula.

When should I check my progress?

Give your routine three consistent months, then compare photos taken in the same light and angle. Every scalp is different; results and timing vary.

When will my order arrive?

We aim for worldwide delivery in around one week. Follow your parcel through the tracking link; customs and remote destinations may take longer.

Excellent4.5/5

Customer reviews

Giorgio V.

The hairline I worried about at school.

My receding hairline had been wearing down my confidence since school. Depura isn’t greasy and takes 30 seconds a day. My hair looked fuller after 10 weeks.

Lorenzo B.

I was only 27.

At 27, I was starting to accept that I’d go bald. Then I found Depura. I can finally enjoy my hair again.

Marco D.

I’d already tried the oils.

I’d wasted money on oils and shampoos that did nothing. With Depura, I noticed the first new hairs within a few weeks and much less shedding.

Luca R., 27

My barber noticed first.

My dad was bald at 30. At 27, I thought I knew what was coming. Five months in, my barber asked what I was using. I hadn’t told him a thing.

Roberto G., 32

I see it in the mirror.

After a month of using the roll-on every evening, I was already shedding less. At three months, my hairline was visibly filling in.

Giorgio M., 29

I thought it was just my DNA.

My father and maternal grandfather were both bald. My crown had been thinning for two years. After two and a half months, the area already looked less empty.

Abasse N.

The first new hairs.

My hair already looks fuller and the first fine new hairs are appearing. It’s very easy to apply along the hairline.

Patrizio P.

No greasy residue.

The blend leaves a pleasant, fresh feeling and takes seconds to apply. No oily residue.

Salvatore D.

A minute, then a gentle massage.

If you’re losing hair, I recommend Depura. Apply it in a minute and massage gently.

English translations of reviews and testimonials published on Depura’s serum page and original roll-on page.